Online Monitoring of Apoptosis in Bioreactor Cell Culture: A Potential Approach
Apoptosis, or programmed cell death, is an essential process in biology and is increasingly becoming a key focus of bioprocess development. Early detection of apoptosis in bioreactor cell cultures is important for controlling and optimizing product yield, as well as understanding the mechanisms of action of certain drugs on cells. One approach to detect apoptosis early within a bioreactor cell culture is through the use of online monitoring techniques. Online monitoring techniques can be used to measure various parameters, including cell viability, cell morphology, and cell density. By measuring these parameters, the process can be monitored throughout the bioprocess development, and any changes in the cell population can be detected. For example, changes in cell morphology, such as an increase in cell size or the appearance of apoptotic bodies, can be used to detect apoptosis (MacMillan et al., 2016). In addition, changes in cell viability or cell density can be used to detect apoptosis, as the number of apoptotic cells in the culture increases. In addition, various techniques can be used to further detect apoptosis within the cell culture. Fluorescent probes, such as Annexin V, can be used to detect the presence of early apoptotic cells, as Annexin V binds to. Cont…
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more