The Biological Rationale Behind DNA Double Strand Breaks in Eukaryotic Cells
DNA double strand breaks (DSB) are the most dangerous type of cellular reaction, carrying a high risk of endangering the life of a cell. As such, much research has gone into understanding the mechanism by which these breaks occur. While DNA DSB can be caused by a variety of external factors, such as radiation exposure or exposure to chemicals, there are also numerous natural processes in eukaryotic cells that produce these breaks. Two of these natural processes are homologous recombination and non-homologous end joining. Homologous recombination is a process in which an exchange of genetic material occurs between two homologous chromosomes. This process is a form of genetic repair, and can result in a double strand break in one or both of the chromosomes (Lisby et al., 2016). Homologous recombination plays a role in the proper functioning of a cell, as it allows for the correction of errors in the genetic material and for the proper functioning of the cell cycle.
Non-homologous end joining is the second natural process that produces DSB in eukaryotic cells. This process is a form of DNA repair that occurs when two broken pieces of DNA are rejoined in a way that does not involve homologous chromosomes (Hendricks et al., 2021). Non-homologous end joining is important for restoring the integrity of the genome and for providing a form of protection against DNA damage. Cont…..
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more