The Use of DNA Microarrays to Identify Genes Involved in the Same Metabolic Pathway
DNA microarrays provide a powerful tool for biologists to identify genes that are involved in the same metabolic pathway. By analysing the expression of genes on the microarray, it is possible to identify genes that are co-regulated and may be involved in the same metabolic pathway. The main steps in using DNA microarrays to find genes involved in the same metabolic pathway include DNA data normalization, DNA clustering, special DNA labeling, and special glass slide techniques. DNA data normalization is the process of adjusting the expression of genes on the microarray so that the data can be compared across different samples. This is achieved by rescaling the expression levels of the genes and normalizing them to a common scale (Chen et al., 2020). DNA clustering uses algorithms to identify clusters of genes that are co-regulated. This allows researchers to identify genes that are likely to be involved in the same metabolic pathway (Wang and Cai, 2021). Cont….
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