How mutations in targets of vaccinations might put a pressure on the need for antivirals and therapies that alleviate deadly symptoms of Covid. There is mentioned an inhibitor for the protease necessary for viral infection to occur. Think together about another possible target for alleviating host infection. As well as, think about how that therapy or treatment idea might affect your own host cells The Impact of Mutations on Vaccine Targets and the Need for Therapies to Alleviate Deadly Covid Symptoms

The Impact of Mutations on Vaccine Targets and the Need for Therapies to Alleviate Deadly Covid Symptoms

The global Covid-19 pandemic has presented a number of challenges, not least of which is the rapid spread of the virus, its mutations, and the need for antivirals and therapies to alleviate its deadly symptoms. While it is true that vaccinations are a key part of the effort to stop the spread of the virus, mutations in the virus can put a pressure on the effectiveness of vaccinations. According to studies published in 2020 and 2021, mutations in the spike protein, which is the target of the majority of vaccines, can “reduce the efficacy of neutralizing antibodies” (Liu et al., 2021; Huang et al., 2020). This means that even when vaccinated, a person may still become infected with the virus. One way that scientists are looking to combat the mutations is to develop therapies that target other areas of the virus. For example, one proposed therapy involves targeting the virus’ protease enzyme, which is necessary for the virus’ infection to occur (Zhang et al., 2021). This would be a powerful antiviral therapy, as it would prevent the virus from replicating. Additionally, scientists are looking for ways to develop therapies that target host cells, rather than the virus itself. Cont….

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