Identify Claire’s aetiology and risk factors and discuss why these, in conjunction with her clinical manifestations, lead to conducting diagnostic tests for this type of diabetes mellitus.

Case Study: Clinical Presentation
Claire Hopkins is a 36 year old female who fractured her leg, due to extensive damage requiring surgery she has been inactive for the past six months. During this time most of her meals were delivered by a company that prepares prepacked meals, though she did have some other groceries delivered for snacks. While inactive she gained weight so has joined a walking group to regain some of her fitness and aid in weight loss, she is finding this challenging as she is often hungry and snacking. Despite drinking the recommended 2 litres of water daily, including when she is walking, she is still thirsty most of the time and consequently urinating frequently. Claire is often tired and fatigued, upon mentioning this to her general practitioner at a routine visit he decides to do some tests to determine why.

Application Question 1
Which of the following clinical manifestations are identifiable in Claire’s case study? Select the most appropriate answer.

Question 1:
Identify the type of diabetes mellitus which Claire has and justify this based on the information in the case study.

Explain the pathophysiology of the disease that Claire has.

Question 2:
List and explain the clinical manifestations which Claire has due to this type of diabetes mellitus.

How are these caused by the changes that occur in the relevant tissues / organs / body systems.

Question 3:
Identify Claire’s aetiology and risk factors and discuss why these, in conjunction with her clinical manifestations, lead to conducting diagnostic tests for this type of diabetes mellitus.

Explain the specific diagnostic procedures conducted on Claire and how the results contribute to her diagnosis.

Question 4:
Explain why the pharmacological treatment, dosage and administration route of the medications prescribed to Claire is appropriate based on her test results.

Outline the mechanism of action by which these medications produce their therapeutic effect in the body.

Identify Claire’s aetiology and risk factors and discuss why these, in conjunction with her clinical manifestations, lead to conducting diagnostic tests for this type of diabetes mellitus.

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