Individuals will sometimes fast for extended periods of time, but they will consume some type of broth (e.g., bone broth). These broths are high in free amino acids. Given that gluconeogenesis becomes the primary means of glucose production during long fasts, please explain why broth is consumed. In your explanation, please use the term “glucose-alanine (or Cahill) cycle.” The Benefits of Broth Consumption During Long Fasts


The Benefits of Broth Consumption During Long Fasts

Intermittent fasting, which involves fasting for extended periods of time, has become increasingly popular in recent years. To reduce hunger pangs during these fasts, many individuals will consume a broth that is high in free amino acids. This consumption is supported by research, as it has been shown to be beneficial during long fasts, particularly when it comes to glucose production. Gluconeogenesis is the primary means of glucose production during long fasts. To explain this phenomenon, the glucose-alanine (or Cahill) cycle has been introduced. This cycle involves an exchange of nitrogen between the muscle and the liver. Specifically, alanine is transported from the muscle to the liver, where it is converted to glucose. The glucose is then transported back to the muscle where it is used for energy.
Due to the fact that broth is high in free amino acids, it helps to facilitate this exchange between the muscle and the liver. This is especially important when it comes to gluconeogenesis as the glucose produced is used to provide energy during long fasts. Cont….

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