The Limitations of Transporter-Mediated Drug Delivery in the Human Body
Transporter-mediated drug delivery is a system of drug delivery that relies on the use of specialized proteins, known as transporters, to facilitate the movement of molecules across cell membranes. This type of drug delivery has the potential to improve drug efficacy, reduce off-target effects, and reduce the need for high doses of medication. However, there are several limitations to transporter-mediated drug delivery that need to be considered when exploring its potential use in humans. One limitation of this type of drug delivery is the limited number of transporters that can be used (Liang & Lai, 2021). For example, the most widely used transporters, the ABC transporters, are only able to transport certain types of molecules. This means that certain drugs may not be able to be delivered using this type of system. Additionally, the expression of transporters can vary from cell to cell, meaning that the efficacy of the drug delivery system may not be consistent across. Cont…
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