The Different Types of Gene Mutations
Gene mutations are changes in the nucleotide sequence of genetic material in an organism. These mutations can be classified into four main types, including point mutations, insertions, deletions, and chromosomal mutations. Point mutations are the most common type of gene mutations, which involve a single nucleotide base substitution. This type of mutation can cause a shift in the genetic code and lead to a change in the amino acid sequence of a protein (Wang, 2019). Insertions are mutations in which additional nucleotides are inserted into the gene. These mutations can cause a frame-shift in the gene, which can lead to the production of a different protein (Wang et al., 2020). Deletions are mutations in which one or more nucleotides are deleted from the gene. This type of mutation can lead to a frame-shift in the gene and a change in the protein produced (Wang et al., 2021).Finally, chromosomal mutations are changes in the structure or number of entire chromosomes. Some of the most common types of chromosomal mutations are deletions, duplications, inversions, and translocations (Gao et al., 2016). Cont….
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