TDP43 Activity does not require condensation according to the evidence
TDP43 (a protein responsible for the regulation of gene transcription, splicing and expression) has been implicated in many neurodegenerative conditions, including amyotrophic lateral sclerosis and frontotemporal dementia (FTD). Although much has been accomplished to determine the role TDP43 plays in these conditions, there are still many unanswered questions. TDP43 activity may require condensation. Recent evidence suggests that TDP43 activitiy does not need condensation. Researchers used a unique approach in order to investigate TDP43 activities. In fact, they found the protein active and functional in absence of condensation in a 2020 paper. The protein could bind to DNA even though it was not condensed. TDP43 activation does not need condensation.
Researchers used cryoelectron microscopy in a 2018 study to analyze the structure and function of TDP43. This indicates that TDP43’s activity is not dependent on condensation. Cont…..
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more