The Regulation of Gene Expression by Environmental Stimuli: A Focus on the Nrf2-ARE Pathway
Gene expression is the process by which genetic information is converted into proteins and other functional molecules. Environmental stimuli can alter gene expression in many ways, such as through the activation of signaling pathways or epigenetic modifications. One example of this is the Nrf2-ARE pathway, which is activated by environmental stressors such as ultraviolet (UV) radiation and oxidative stress (Hassan, 2020). The Nrf2-ARE pathway is a transcriptional regulatory system that responds to environmental stressors by upregulating the expression of a variety of cytoprotective and antioxidant genes (Yoon et al., 2017). When exposed to an environmental stressor, Nrf2 is released from its inhibitory complex and translocates to the nucleus where it binds to antioxidant response elements (AREs) that are present in the promoters of target genes (Hassan, 2020). This leads to the upregulation of those genes and the production of cytoprotective and antioxidant proteins (Yoon et al., 2017). The Role of Nrf2 in Regulating the Expression of Genes in Response to Environmental Stressors
. The gene Nrf2 (Nuclear factor erythroid 2-related factor 2) plays an important role in regulating the expression of genes in response to environmental stressors. Nrf2 is a transcription factor that is activated when exposed to an environmental stressor. Cont….
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.
Read moreEach paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.
Read moreThanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.
Read moreYour email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.
Read moreBy sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.
Read more