The Role of Cyclin-Dependent Kinases (CDKs) in Cell Cycle Stages: True or False?
Cyclin-Dependent Kinases (CDKs) are a family of enzymes that play a key role in the regulation of cell cycle progression. They initiate each aspect of each cell cycle stage through phosphorylation of various target proteins. This process is essential for the orderly and timely progression of the cell cycle, ensuring the proper duplication and segregation of genetic material. Recent studies have demonstrated that CDKs are required for the proper control of all cell cycle stages (Gómez-López et al., 2019; Zhou et al., 2020). The activity of CDKs is regulated by the binding of cyclins, regulatory proteins that help control their activity by increasing and decreasing the activity of the CDKs. As cells progress through the cell cycle, the cyclins increase and decrease, regulating the activity of the CDKs (Fry et al., 2016). This allows for the proper progression of the cell cycle, and helps ensure that proper replication of genetic material occurs. Cont…
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