The Probability of Having a Red-Green Colorblind Girl Who is a Carrier for AT: Exploring the Genetics of X-Linked Disorders
One of the most commonly inherited genetic disorders, red-green colorblindness, is carried on the X-chromosome in a recessive pattern. In this scenario, a red-green colorblind man who is also a carrier for ataxia telangiectasia (AT) is married to a normal-vision woman who is not affected by AT and does not carry the allele for the disorder. Their two children, a boy and a girl, are both normal-vision and red-green colorblind, respectively. Fortunately, neither child was diagnosed with AT. Given the information provided in this scenario, the probability of having a red-green colorblind girl who is a carrier for AT is 25%. Since the man is a carrier for AT, each of his children inherits a 50% chance of being a carrier for the disorder (Miyamoto et al., 2016). Since the daughter inherits the X-chromosome from her father, she also has a 50% chance of inheriting the colorblindness gene (Klein et al., 2020). Therefore, the combination of these two probabilities gives the probability of having a red-green colorblind daughter who is a carrier for AT as 25%. Cont…
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