Red-green colorblindness is another genetic disorder, but is carried recessively on the X-chromosome. A red-green colorblind man who is a carrier for ataxia telangiestasia (AT) is married to a normal-vision woman who is not affected by AT, and does not carry the allele for the disorder. They have two children, a boy who is normal-vision and a girl who is red-green colorblind. Fortunately, neither child was diagnosed with AT. What is the probability that their next child will be a red-green colorblind girl who is a carrier of the allele for AT? The Probability of Having a Red-Green Colorblind Girl Who is a Carrier for AT: Exploring the Genetics of X-Linked Disorders

The Probability of Having a Red-Green Colorblind Girl Who is a Carrier for AT: Exploring the Genetics of X-Linked Disorders

One of the most commonly inherited genetic disorders, red-green colorblindness, is carried on the X-chromosome in a recessive pattern. In this scenario, a red-green colorblind man who is also a carrier for ataxia telangiectasia (AT) is married to a normal-vision woman who is not affected by AT and does not carry the allele for the disorder. Their two children, a boy and a girl, are both normal-vision and red-green colorblind, respectively. Fortunately, neither child was diagnosed with AT. Given the information provided in this scenario, the probability of having a red-green colorblind girl who is a carrier for AT is 25%. Since the man is a carrier for AT, each of his children inherits a 50% chance of being a carrier for the disorder (Miyamoto et al., 2016). Since the daughter inherits the X-chromosome from her father, she also has a 50% chance of inheriting the colorblindness gene (Klein et al., 2020). Therefore, the combination of these two probabilities gives the probability of having a red-green colorblind daughter who is a carrier for AT as 25%. Cont…