The Old Paradigm for Molecular Genetics: Exploring the Impact of Changing Technologies
Molecular genetics is the study of the structure, function, and transmission of genetic material. It is a relatively new field of science, with the first significant advances in the field being made in the 1950s and 1960s. However, the old paradigm for molecular genetics was largely based on the use of a few basic techniques and technologies, including restriction fragment length polymorphism (RFLP), Southern blotting, and polymerase chain reaction (PCR) (Bhattacharya et al., 2022). These methods provided the foundation for much of the early research in the field and enabled scientists to make many important discoveries. RFLP was one of the earliest methods used in the field and relied on the analysis of genetic variation within a population of organisms. By comparing the lengths of restriction fragments in different individuals, researchers could identify genetic variations that were associated with certain traits (Gibbs, 2016). Southern blotting was another important method used in the field and relied on the use of radioactively labeled probes to detect. Cont…
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