The Molecule That Is Not a Part of Nucleotide-Exision Repair
Nucleotide-excision repair (NER) is a primary pathway for removing damaged or otherwise misaligned DNA bases from a genome. It is a sophisticated, multi-step process that involves the recognition of damaged or misaligned bases, the excision of the affected section, and the repair of the resultant gap. This process is incredibly important for genetic stability and is found in many organisms, including humans. Many molecules are involved in the process, but one stands out as not being a part of NER. Adenosine triphosphate (ATP) is an essential molecule in many biological processes, including NER. It is the energy currency of cells, providing the energy to drive a variety of processes, including DNA repair. However, unlike the other molecules involved in NER (such as polymerase and helicase), ATP is not a part of the actual repair process. Instead, it provides the energy to drive the other molecules involved. As such, it is not technically a part of NER and is instead an essential enabling molecule. Cont…
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